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Advisors

Doug Cameron

Founder & Managing Director Alberti Advisors,LLC

Dr. Douglas (Doug) Cameron is Co-President and Director of First Green Partners, an early-stage investment company focused on the carbon value chain, based in Minneapolis. Prior to First Green Partners, Doug founded Alberti Advisors, where he consulted with a range of companies at the interface between agriculture and energy.

He was also an investment banker at Piper Jaffray and the chief scientific officer at Khosla Ventures. In 1998, Doug started the corporate biotechnology research group at Cargill and directed the group for 8 years. Before joining Cargill, he spent 12 years as a professor of chemical engineering at the University to Wisconsin-Madison where he taught and did research in metabolic engineering and biochemical engineering.

John Cronan

University of Illinois, Urbana-Champaign

John Cronan is Alumni Professor of Microbiology and Professor of Biochemistry at the University of Illinois, Urbana-Champaign. He also serves as Head of the Department of Microbiology. Dr. Cronan's research has focused on the biosynthesis and degradation of lipids in bacteria. He pioneered genetic approaches to understanding the mechanisms and regulation of bacterial lipid metabolism and is a leading expert on fatty acid biosynthesis. Dr. Cronan and his group have also studied pathways closely related to lipid metabolism including two-carbon metabolism and the synthesis of cofactors derived from (or essential to) fatty acid biosynthesis. In this latter work they discovered the pathway whereby the key metabolic cofactor, lipoic acid, is synthesized and attached to its cognate proteins and have also made important contributions to understanding the biotin and CoA biosynthetic pathways.

Dr. Cronan has extensive experience with a variety of host organisms including E. coli, the subject of much of his research. He and his group have authored over 300 research papers and reviews. Dr. Cronan is a member of the American Academy of Microbiology. He has served as a consultant to a wide variety of bioscience, chemical, and pharmaceutical companies. Dr. Cronan received his B.A. in Biology from California State University, Northridge and his Ph.D. in Molecular Biology from the University of California, Irvine. Before joining the facility at the University of Illinois at Urbana-Champaign, he completed postdoctoral studies in biochemistry at the Washington University School of Medicine and served as Assistant and Associate Professor of Biochemistry at Yale University.

Chaitan Khosla

Stanford University

Chaitan Khosla is Professor of Chemistry, Chemical Engineering, and, by courtesy, of Biochemistry at Stanford University. Over the past two decades, Dr. Khosla has studied polyketide synthases as paradigms for modular catalysis, and has exploited their properties for engineering novel antibiotics. More recently, he has investigated celiac sprue pathogenesis with the goal of developing drug therapies for this widespread but overlooked disease.

He has co-authored over 200 publications, and is the recipient of several awards and honors including a National Science Foundation Young Investigator Award, a David and Lucile Packard Fellowship for Science and Engineering, the Allan P. Colburn Award from the American Institute of Chemical Engineers, the Eli Lilly Award in Biological Chemistry and the Pure Chemistry Award from the American Chemical Society, and the Alan T. Waterman Award from the National Science Foundation. He is also the recipient of a Distinguished Alumnus Award from his undergraduate and graduate alma maters.

Dr. Khosla is a founder of Kosan Biosciences, a public pharmaceutical company that develops polyketide drugs. He was also the founding president of the non-profit Celiac Sprue Research Foundation, and is a founder of Alvine Pharmaceuticals, a privately held company that develops drugs for celiac sprue. Dr. Khosla received a B.S. Tech. from the Indian Institute of Technology, Bombay, India and a Ph.D. from the California Institute of Technology. After completing postdoctoral studies at the John Innes Centre in the UK, he joined Stanford in 1992.

Uwe Sauer

Swiss Federal Institute of Technology (ETH) Zurich

Uwe Sauer is Professor of Systems Biology in the Department of Biology at the ETH Zurich. He is a well-recognized expert on central metabolism of bacteria and yeast. Research in the Sauer lab is focused on an interdisciplinary approach that combines quantitative experimentation and modeling to solve fundamental questions of complex metabolic network operation and to engineer general cellular functions such as redox and energy metabolism. In particular, his lab has pioneered methods for 13C-flux analysis and is a key player in quantitative metabolomics.

Dr. Sauer has over 70 publications over the last 5 years, and is a member of various international editorial boards, scientific steering and advisory committees of international organizations and companies in systems biology and biotechnology. He earned his M.S. and Ph.D. in microbiology from the University of Göttingen.

Anthony Sinskey

Massachusetts Institute of Technology

Anthony Sinskey is Professor of Microbiology in the Department of Biology and Health Sciences and Technology at the Massachusetts Institute of Technology. He is a well recognized expert on metabolic pathway engineering, including transgenic methods for polymer production. Research in the Sinskey lab is focused on an interdisciplinary approach to metabolic engineering, focusing on the fundamental physiology, biochemistry and molecular genetics of important organisms. In particular, his team is studying key factors that regulate the synthesis of different biomolecules.

Dr. Sinskey is recognized as a leading expert in the formation of new biotechnology enterprises and a renowned academic entrepreneur. He has participated in the founding and development of over 10 biotechnology companies including Metabolix, Genzyme, Tepha, ABEC, Merrimack Pharmaceuticals and serves on the board of directors and advisory boards of eight companies. Dr. Sinskey earned a B.S. from the University of Illinois and a Sc.D. from MIT. He completed his Post Doctoral Fellowship at the Harvard School of Public Health.

Christopher Stone

Advisor to the Board

Christopher Stone is an advisor to the Board and has over 17 years of legal and intellectual property experience, including 12 years of experience in industrial biotechnology. Mr. Stone has previously held the roles of Vice President, Intellectual Assets at Danisco A/S and Vice President, General Patent Counsel at Genencor International, Inc. Mr. Stone's responsibilities have included intellectual property protection and management, contract negotiation and drafting, participation in business operations and strategic planning, and litigation management.

Mr. Stone received his J.D. from the George Washington University, National Law Center and a B.S., Biochemistry, from the University of Massachusetts.

Christopher Walsh

Harvard Medical School

Christopher Walsh is Hamilton Kuhn Professor at Harvard Medical School and a former President of the Dana-Farber Cancer Institute and Chairman of the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. He is an expert in enzyme stereochemistry and reaction mechanisms. His research has focused on enzymes and enzyme inhibitors, with recent specialization on antibiotics and biosynthesis of other biologically active natural products. He and his group have authored over 645 research papers, books onEnzymatic Reaction Mechanisms(1979);Antibiotics: Origins, Actions, Resistance(2003);Posttranslational Modification of Proteins: Expanding Nature's Inventory(2005). He is a member of the National Academy of Sciences, the Institute of Medicine, the American Academy of Arts and Sciences, and the American Philosophical Society.

Dr. Walsh is also a member of the board of directors of Critical Therapeutics, Kosan Biosciences, and several private companies. He received a B.A. in Biology from Harvard University and a Ph.D. in Life Sciences from Rockefeller University.